Volume 6, Issue 1, January 2020, Page: 1-6
Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences
Adnan Shah, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Attiya Hameed Khan, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Hammad Ahmed, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Aamir Naveed, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Faridullah Khan, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Javeed Iqbal, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Adnan Tahir, Department of Cardiac Surgery at Pakistan Institute of Medical Sciences, Bashir Institute of Health Sciences Affiliated with Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan
Received: Nov. 19, 2019;       Accepted: Dec. 18, 2019;       Published: Feb. 4, 2020
DOI: 10.11648/j.ijcts.20200601.11      View  472      Downloads  163
Abstract
This study compares post-operative outcomes for ionotropic support, defibrillator need and duration of hospital stay in adult patients of cardiac surgery following Del Nido cardioplegia versus Howard’s cardioplegia and also compare pre and post operative Cardiac enzymes and serum potassium levels, assessment of pre and post operative Arrthymias. It was an Observational study conducted at Pakistan Institute of Medical Sciences Islamabad Pakistan. Patients were divided into 2 groups. Group (A) patients were Del Nido cardioplegia and Group (B) patients were Howard’s cardioplegia. Data was collected by using non-probability Consecutive Sampling technique. 100 patients were enrolled in this study randomly allocating 50 to each study group. Results of the study show that Post-op CKMB level after 24 hours for Howard group was (127.5200±103.59069) and for DN group (67.3540±23.21292). Similarly post op Potassium level for Howard group was (4.9742±.77010) and for DN group was (4.5590±.65033), Duration of hospital stay for Howard’s group was (9.60±.857) and for DN group was (8.58±1.486). High ionotropic support was required in Howard’s group as compared to DN where it was mild to moderate. 40% patients required defibrillation in Howards as compared to DN with only 20%. It is concluded that Cardioplegia is intended for brief cardiac arrest, which is an important function during cardiopulmonary Bypass surgery. After comparing two cardioplegic solutions namely Del Nido and Howard’s cardioplegia. Our study concludes that Del-Nido cardioplegia provide better myocardial protection and less cross clamp and bypass time. Cardiac enzymes, serum potassium level and post-op arrthymias show better profile in Del-Nido as compared to Howard’s cardiolpegia. Our data clearly advocate the efficacy and safety of Del-Nido over Howard’s cardioplegia. It is very safe and effective as compared to Howards.
Keywords
Cardiopulmonary Bypass, Coronary Artery Disease, Adult Cardiac Surgery, Cardioplegia, Howards, Del-Nido, Cardiac Enzymes
To cite this article
Adnan Shah, Attiya Hameed Khan, Hammad Ahmed, Aamir Naveed, Faridullah Khan, Javeed Iqbal, Adnan Tahir, Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences, International Journal of Cardiovascular and Thoracic Surgery. Vol. 6, No. 1, 2020, pp. 1-6. doi: 10.11648/j.ijcts.20200601.11
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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