Volume 6, Issue 4, July 2020, Page: 49-55
Platelets Count During Circulatory Assistance: Involvement in the Changes of Oxygenation Membrane
Adama Sawadogo, Department of Cardiovascular Surgery, University of Clermont-Auvergne, Clermont-Ferrand, France; Department of Cardiovascular and Thoracic Surgery, University Hospital of Tengandogo, Ouagadougou, Burkina Faso
Alaa Azhari, Department of Cardiovascular Surgery, University of Clermont-Auvergne, Clermont-Ferrand, France
Nicolas D’Ostrevy, Department of Cardiovascular Surgery, University of Clermont-Auvergne, Clermont-Ferrand, France
Celine Lambert, Department of Biostatistics, University of Clermont-Auvergne, Clermont-Ferrand, France
Bruno Pereira, Department of Biostatistics, University of Clermont-Auvergne, Clermont-Ferrand, France
Kasra Azarnoush, Department of Cardiovascular Surgery, University of Clermont-Auvergne, Clermont-Ferrand, France
Lionel Camilleri, Department of Cardiovascular Surgery, University of Clermont-Auvergne, Clermont-Ferrand, France
Received: Jun. 15, 2020;       Accepted: Jun. 24, 2020;       Published: Aug. 20, 2020
DOI: 10.11648/j.ijcts.20200604.11      View  240      Downloads  44
Abstract
Background: Membrane Oxygenation (MO) complication events during ECMO have decreased in recent decades due to improved coatings and biocompatible materials. The authors studied the evolution of platelet count during Extra-Corporeal Membrane Oxygenation (ECMO) and the causes of MO exchange. Results: Mean age was 56.8±13.4 years. Mean duration of the MO was 5.9±3.1 days, exchanged 26 times (68%) after clot formation. A decrease (p<0.001) in platelet count between the first and second MO exchange was observed in comparison with the baseline. The decrease on day 2 was significant (p<0.001), the delta was 58.000±19.000/µL, followed by a decrease on day 3 (p=0.001). A steady decline was noted after the third MO exchange, afterwards, normalization was observed after ECMO weaning. The average platelet transfusion was 0.6±1.4 units. The more MO was exchanged, the lesser blood products transfusion was done. The overall mortality rate was 39%. Conclusion: The platelets count decreases significantly on day 2 in patients who have being treated with circulatory assistance. Prediction of the need for MO exchange implies circuit checking and the study of hemolysis, coagulation, and hemostasis parameters.
Keywords
Platelets, Membrane Oxygenation, ECMO, SAVE Score, RESP Score, Cardiac Surgery
To cite this article
Adama Sawadogo, Alaa Azhari, Nicolas D’Ostrevy, Celine Lambert, Bruno Pereira, Kasra Azarnoush, Lionel Camilleri, Platelets Count During Circulatory Assistance: Involvement in the Changes of Oxygenation Membrane, International Journal of Cardiovascular and Thoracic Surgery. Vol. 6, No. 4, 2020, pp. 49-55. doi: 10.11648/j.ijcts.20200604.11
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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