Evolution of Bioprosthetic Valves, Where We Are Heading
Issue:
Volume 9, Issue 5, September 2023
Pages:
63-66
Received:
4 September 2023
Accepted:
25 September 2023
Published:
8 October 2023
Abstract: Bioprosthetic heart valves are made from animal tissue and used to replace damaged or diseased heart valves. The first bioprosthetic valve was implanted in 1960, and since then, there have been significant advances in their design and development. Early valves were made from glutaraldehyde-preserved porcine valves and had a high risk of calcification. In the 1980s, cryopreserved porcine valves were introduced, which are less likely to calcify. Tissue-engineered heart valves, made from cells and tissues grown in the lab, are still in development but have the potential to offer longer lifespans and lower risk of rejection. Continuous research and development are happening to improve design, swing ring, cuff size, ring material, storage solution, rinsing time, anticalcification treatment, ease of implant for surgeons, and making these valves future ready for interventional procedures. Currently we are having fourth generation of these valves (Company classification). The evolution of bioprosthetic heart valves has led to improved outcomes for patients with heart valve disease. These valves are now a standard treatment option and offer a good quality of life and long-term survival. Initial results of both bovine fourth generation bioprosthetic valves Medtronic Avalus (PERIGON trial) and Edwards Inspiris resilia (COMMENCE trial) are good. The evolution of bioprosthetic heart valves is an ongoing process. As new technologies are developed, these valves are likely to become even more durable and effective.
Abstract: Bioprosthetic heart valves are made from animal tissue and used to replace damaged or diseased heart valves. The first bioprosthetic valve was implanted in 1960, and since then, there have been significant advances in their design and development. Early valves were made from glutaraldehyde-preserved porcine valves and had a high risk of calcificati...
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Isolated Right Atrial Appendage Rupture from Blunt Chest Trauma: A Case Report
Tran Thuc Khang,
Huynh Khiem Huy,
Bui Trong Dat,
Dang Le Hong Ngan,
Trinh Cong Dong,
Tran Quang Thai
Issue:
Volume 9, Issue 5, September 2023
Pages:
67-70
Received:
13 September 2023
Accepted:
5 October 2023
Published:
14 October 2023
Abstract: Background: Right atrial appendage rupture from blunt trauma is very uncommon, but is associated with a high mortality rate. Moreover, due to the paucity in available literature, our knowledge of the condition is still limited. Purposes: To emphasize a high degree of clinical suspicion in a case of cardiac tamponade after blunt chest trauma, quick diagnostic confirmation and urgent optimal management of such cases to save the patient and to avoid unnecessary and unacceptable delays. Case presentation: The author reports a 22-year-old female involved in a blunt chest trauma who was initially misdiagnosed and delayed management in a regional hospital, then transferred to our institution in a status of severe hypovolemic shock and cardiac tamponade with unconsciousness, intubation and mildly dilated and weakly reactive eyes/pupils. Fortunately, the patient was saved with quick diagnostic confirmation, urgent sternotomy and surgical repair of atrial appendage laceration for hemostasis associated with intra- and post-operatively intensive resuscitations. Conclusion: The important key to right atrial rupture diagnosis is a high degree of clinical suspicion in a case of cardiac tamponade following blunt chest trauma, especially with a hemodynamically unstable or compromised status. Aggressive resuscitation, prompt diagnosis, and urgent operation to repair the cardiac lesions are cornerstones to achieving an optimal outcome.
Abstract: Background: Right atrial appendage rupture from blunt trauma is very uncommon, but is associated with a high mortality rate. Moreover, due to the paucity in available literature, our knowledge of the condition is still limited. Purposes: To emphasize a high degree of clinical suspicion in a case of cardiac tamponade after blunt chest trauma, quick ...
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